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KMID : 0614619950270040481
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Korean Journal of Gastroenterology
1995 Volume.27 No. 4 p.481 ~ p.487
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A Case of Amyloidosis Associated with malignant Lymphoma, Presenting as a Malabsorption Syndrome
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김태헌
김재규/장유현/송상용/정현태/송인성/조한익/김용일/최규완
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Abstract
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Amyloidosis is known as a disease that affects almost all organs, and may especially cause widespread damage to the gastrointestinal tract. Intestinal amyloid may cause motility disturbances with diarrhea or constipation, malabsorption, bleeding,
and
perforation. We report a case of systemic amyloidosis presenting as a malabsorption syndrome. A 59-year old woman with abdominal pain and chronic diarrhea turned out to have malignant lymphoma, GI amyloidosis, monoclonal gammopathy, and
malabsorption
syndrome, Well differentiated lymphocytic lymphoma was diagnosed by bone marrow biopsy. Endoscopic biopsy tissues from duodenum and rectum showed typical electron microscopic and staining features of amyloidosis. Serum protein electrophoresis
revealed
IgG λ monoclonal gammopathy. D-xylose test and α1-trypsin clearance test confirmed malabsorption and protein-losing enteropathy, respectively. (Korean J Gastroenterol 1995; 27: 481-487)
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KEYWORD
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